JAK3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | JAK3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Direct ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for JAK3 detection. Tested with WB, Direct ELISA in Human.Background: Tyrosine-protein kinase JAK3 is an enzyme that in humans is encoded by the JAK3 gene. It is mapped to 19p13.11. The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). |
| Immunogen | Immunogen: E Coli-derived human JAK3 recombinant protein (Position: Q406-D661). Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Relevant Detection Systems: Relevant Detection Systems: We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (MBS176460) for Western blot. |
| Other Names | [Tyrosine-protein kinase JAK3; Janus kinase 3; Tyrosine-protein kinase JAK3; Janus kinase 3; JAK-3; Leukocyte janus kinase; L-JAK; JAK3] |
| Gene, Accession # | [JAK3], Gene ID: 3718, NCBI: NP_000206.2, UniProt: P52333 |
| Catalog # | MBS1752492 |
| Price | $280 |
| Order / More Info | JAK3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Riedy MC, Dutra AS, Blake TB, Modi W, Lal BK, Davis J, Bosse A, O'Shea JJ, Johnston JA (October 1996). Genomic sequence, organization, and chromosomal localization of human JAK3. Genomics. 37 (1): 57-61. 2. Hoffman SM, Lai KS, Tomfohrde J, Bowcock A, Gordon LA, Mohrenweiser HW (July 1997). JAK3 maps to human chromosome 19p12 within a cluster of proto-oncogenes and transcription factors. Genomics. 43 (1): 109-11. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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