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Antigenic Specificity | Delta like 3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted: rat |
Isotype | n/a |
Format | Protein A purified |
Size | 0.025 mg, 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Delta like 3 (DLL3) is a member of Delta/Serrate/Lag2 (DSL) ligands for Notch receptors and plays a role in Notch signaling. Out of Five DSL ligands, DLL3 is the most structurally divergent DSL ligand. DLL3 is expressed throughout the presomitic mesoderm and is localized to the rostral somatic compartments. Homozygous disruptions of Notch1 and DLL3 result in severe abnormalities in somitogenesis. Mutations in the human DLL3 homolog cause recessive skeletal abnormalities in spondylocostal dysostosis with a consistent pattern of abnormal segmentation. |
Immunogen | Immunogen Information: A partial length recombinant Delta like 3 protein (amino acids 62-286) was used as the immunogen for this antibody. |
Other Names | [DLL3; Drosophila Delta homolog 3; to Delta like 3; Delta like 3; Delta like 3], [DLL3; DLL3; SCDO1; Delta3] |
Gene, Accession # | [DLL3], Gene ID: 10683, NCBI: Q9NYJ7.1, UniProt: Q9NYJ7 |
Catalog # | MBS668623 |
Price | $140, $270 |
Order / More Info | Delta like 3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |