ATG4A Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | ATG4A |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total ATG4A protein. Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms.Marino G., J. Biol. Chem. 278:3671-3678(2003).Kabeya Y., J. Cell Sci. 117:2805-2812(2004).Ross M.T., Nature 434:325-337(2005 |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from C-terminal of human ATG4A. |
| Other Names | [Cysteine protease ATG4A; EC 3.4.22.-; Autophagy-related protein 4 homolog A; hAPG4A; Autophagin-2] |
| Gene, Accession # | [ATG4A], Gene ID: 115201, NCBI: NP_443168.2, UniProt: Q8WYN0 |
| Catalog # | MBS9411496 |
| Price | $200, $255 |
| Order / More Info | ATG4A Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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