PYCARD (C-term), 129-158 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPYCARD (C-term), 129-158
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationn/a
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis PYCARD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 129-158 amino acids from the C-terminal region of human PYCARD. This gene encodes an adaptor protein that is composed oftwo protein-protein interaction domains: a N-terminalPYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitmentdomain (CARD). The PYD and CARD domains are members of thesix-helix bundle death domain-fold superfamily that mediatesassembly of large signaling complexes in the inflammatory andapoptotic signaling pathways via the activation of caspase. Innormal cells, this protein is localized to the cytoplasm; however,in cells undergoing apoptosis, it forms ball-like aggregates near
Immunogenn/a
Other Names[Apoptosis-associated speck-like protein containing a CARD; hASC; Caspase recruitment domain-containing protein 5; PYD and CARD domain-containing protein; Target of methylation-induced silencing 1; PYCARD; ASC; CARD5; TMS1]
Gene, Accession #[PYCARD], Gene ID: 29108, NCBI: NP_037390.2, UniProt: Q9ULZ3
Catalog #MBS9207503
Price$165, $370
Order / More InfoPYCARD (C-term), 129-158 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesGrau, E., et al. J. Cancer Res. Clin. Oncol. 136(9):1415-1421(2010) Motani, K., et al. Cancer Sci. 101(8):1822-1827(2010) Mishra, B.B., et al. Cell. Microbiol. 12(8):1046-1063(2010) Cheng, J., et al. J. Cell. Physiol. 222(3):738-747(2010) McElvania Tekippe, E., et al. PLoS ONE 5 (8), E12320 (2010) :
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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