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Antigenic Specificity | PYCARD (C-term), 129-158 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PYCARD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 129-158 amino acids from the C-terminal region of human PYCARD. This gene encodes an adaptor protein that is composed oftwo protein-protein interaction domains: a N-terminalPYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitmentdomain (CARD). The PYD and CARD domains are members of thesix-helix bundle death domain-fold superfamily that mediatesassembly of large signaling complexes in the inflammatory andapoptotic signaling pathways via the activation of caspase. Innormal cells, this protein is localized to the cytoplasm; however,in cells undergoing apoptosis, it forms ball-like aggregates near |
Immunogen | n/a |
Other Names | [Apoptosis-associated speck-like protein containing a CARD; hASC; Caspase recruitment domain-containing protein 5; PYD and CARD domain-containing protein; Target of methylation-induced silencing 1; PYCARD; ASC; CARD5; TMS1] |
Gene, Accession # | [PYCARD], Gene ID: 29108, NCBI: NP_037390.2, UniProt: Q9ULZ3 |
Catalog # | MBS9207503 |
Price | $165, $370 |
Order / More Info | PYCARD (C-term), 129-158 Antibody from MYBIOSOURCE INC. |
Product Specific References | Grau, E., et al. J. Cancer Res. Clin. Oncol. 136(9):1415-1421(2010) Motani, K., et al. Cancer Sci. 101(8):1822-1827(2010) Mishra, B.B., et al. Cell. Microbiol. 12(8):1046-1063(2010) Cheng, J., et al. J. Cell. Physiol. 222(3):738-747(2010) McElvania Tekippe, E., et al. PLoS ONE 5 (8), E12320 (2010) : |