Mouse CD3z Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse CD3z |
| Clone | [H146-968] |
| Host Species | Hamster |
| Reactive Species | mouse |
| Isotype | IgG2kappa |
| Format | biotin conjugate |
| Size | 0.1 mg, 0.3 mg |
| Concentration | Antibody concentration: 0.1 mg/ml |
| Applications | Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: CD3z (CD247) (Mouse CD3z (zeta chain); also known as CD247). The TCR complex consists of a ligand specific alpha/beta heterodimer non-covalently associated with five invariant chains including the CD3 gamma, delta, eta and zeta subunits. This complex regulates assembly and expression of the receptor and is thought to be responsible for transmembrane transduction of signals after binding to TCRalphabeta. Studies have suggested that the CD3z subunit (also know as CD247) plays an important role in two distinct cellular compartments. In the cytoplasm, it may function to regulate Ag receptor expression and in the plasma membrane it may be required for optimal signaling by the physiologic ligand Ag/MHC. The CD3z subunit is also assoc |
| Immunogen | Immunogen: KLH conjugated mouse zeta-chain (CD3) sequence 151-164. Donor: Armenian hamster |
| Other Names | [CD3z, Biotin (Clone H146-968) (hamster IgG); Biotin Mouse CD3z (CD247)], [CD247; CD247; T3Z; CD3H; CD3Q; CD3Z; TCRZ; CD3-ZETA; CD3Z; T3Z; TCRZ] |
| Gene, Accession # | [CD3z], Gene ID: 919, NCBI: AAY57330.1, UniProt: P20963 |
| Catalog # | MBS520100 |
| Price | $235, $430 |
| Order / More Info | Mouse CD3z Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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