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Antigenic Specificity | Rac1 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Ras-related C3 botulinum toxin substrate 1(RAC1) detection. Tested with WB in Human;Mouse;Rat. Background: Rac1, also known as Ras-related C3 botulinum toxin substrate 1, is a protein found in human cells. It is encoded by the RAC1gene. This gene can produce a variety of alternatively splicedversions of the Rac1 protein, which appear to carry out different functions. This gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms h |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Rac1 (169-189aa FDEAIRAVLCPPPVKKRKRKC), identical to the related mouse and rat sequences. Ig Type: Rabbit IgG |
Other Names | [Ras-related C3 botulinum toxin substrate 1; Cell migration inducing gene 5 protein; Cell migration-inducing gene 5 protein; MGC111543; MIG5; Migration inducing gene 5; Migration inducing protein 5; p21 Rac1; p21-Rac1; Rac 1; RAC1; RAC1_HUMAN; Ras like protein TC25; Ras related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); Ras-like protein TC25; Ras-related C3 botulinum toxin substrate 1; Rho family small GTP binding protein Rac1; TC 25; TC25; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)], [RAC1; RAC1; MIG5; Rac-1; TC-25; p21-Rac1; TC25] |
Gene, Accession # | [RAC1], Gene ID: 5879, NCBI: NP_008839.2, UniProt: P63000 |
Catalog # | MBS177808 |
Price | $280 |
Order / More Info | Rac1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Didsbury J, Weber RF, Bokoch GM, Evans T, Snyderman R (October 1989). rac, a novel ras-related family of proteins that are botulinum toxin substrates. J. Biol. Chem. 264 (28): 16378-82. 2. Jordan P, Brazao R, Boavida MG, Gespach C, Chastre E (November 1999). Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors.Oncogene 18 (48): 6835-9. 3. Zhou C, Licciulli S, Avila JL, Cho M, Troutman S, Jiang P, Kossenkov AV, Showe LC, Liu Q, Vachani A, Albelda SM, Kissil JL (February 2013). The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis. Oncogene 32 (7): 903-9. |