RASGRP2 (N-term) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRASGRP2 (N-term)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size0.05 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis RASGRP2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 108-142 amino acids from the N-terminal region of human RASGRP2. Functions as a calcium- and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. May also activates other GTPases such as RRAS, RRAS2, NRAS, KRAS but not HRAS. Functions in aggregation of platelets and adhesion of T-lymphocytes and neutrophils probably through inside-out integrin activation. May function in the muscarinic acetylcholine receptor M1/CHRM1 signaling pathway.
Immunogenn/a
Other Names[Purified Rabbit (Pab); RAS guanyl-releasing protein 2; Calcium and DAG-regulated guanine nucleotide exchange factor I; CalDAG-GEFI; Cdc25-like protein; hCDC25L; F25B33 kinase-like protein; RASGRP2; CDC25L; MCG7]
Gene, Accession #[RASGRP2], Gene ID: 10235, NCBI: NP_001092140.1, UniProt: Q7LDG7
Catalog #MBS9215810
Price$150
Order / More InfoRASGRP2 (N-term) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesKedra D.,et al.Hum. Genet. 100:611-619(1997).Kawasaki H.,et al.Proc. Natl. Acad. Sci. U.S.A. 95:13278-13283(1998).Clyde-Smith J.,et al.J. Biol. Chem. 275:32260-32267(2000).Ota T.,et al.Nat. Genet. 36:40-45(2004).Taylor T.D.,et al.Nature 440:497-500(2006).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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