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Antigenic Specificity | Caspase-7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Caspase-7 Polyclonal Antibody detects endogenous levels of Caspase-7 protein. CASP7 encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of caspase 7 is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human Caspase-7 at AA range: 160-240 |
Other Names | [Rabbit Caspase-7; MCH3; Caspase-7; CASP-7; Apoptotic protease Mch-3; CMH-1; ICE-like apoptotic protease 3; ICE-LAP3] |
Gene, Accession # | [CASP7], Gene ID: 840, NCBI: NP_001218.1, UniProt: P55210 |
Catalog # | MBS9700618 |
Price | $250, $250 |
Order / More Info | Caspase-7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |