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Antigenic Specificity | DYRK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mg |
Concentration | 0.5 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Overview: May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Modulates alternative splicing by phosphorylating the splice factor SRSF6. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates such as CRY2, FOXO1, SRSF6 and SIRT1. Exhibits a sugstrate preference for proline at position P+1 and arginine at position P-3.Structure: The polyhistidine repeats act as targeting signals to nuclear speckles.Expression: Ubiquitous. Highest levels in skeletal muscle, testis, fetal lung and fetal kidney. |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 300-350 on human Dual specificity tyrosine-phosphorylation-regulated kinase 1A. Conjugation: Unconjugated |
Other Names | [Affinity Purified Dual specificity tyrosine-phosphorylation-regulated kinase 1A; Dual specificity tyrosine phosphorylation regulated kinase; Dual specificity YAK1-related kinase; DYRK; DYRK1; DYRKA; hMNB; HP86; Minibrain, Drosophila, homolog of MNB; MNB protein kinase; Mnb protein kinase homolog hp86; MNB protein kinase, Serine/threonine-specific; MNB/DYRK protein kinase; MNBH; MRD7; Protein kinase minibrain homolog; Serine/threonine kinase MNB] |
Gene, Accession # | [DYRK1], Gene ID: 1859, NCBI: NP_001334650.1, UniProt: Q13627 |
Catalog # | MBS5400389 |
Price | $390 |
Order / More Info | DYRK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |