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Antigenic Specificity | ABI1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 2mg/mL |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10; 11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced tran |
Immunogen | Immunogen: Synthetic peptide of human ABI1 |
Other Names | [E3B1; ABI-1; ABLBP4; NAP1BP; SSH3BP; SSH3BP1] |
Gene, Accession # | [ABI1], Gene ID: 10006, NCBI: NP_001171595.1 |
Catalog # | MBS2517857 |
Price | $110, $150, $225 |
Order / More Info | ABI1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |