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Antigenic Specificity | NES |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Nestin is an intermediate filament family member protein that is structurally related to the neurofilament proteins (1). It is highly expressed in the developing brain, where it may help to regulate cell structure and intracellular processes required for neural cell division and migration (1,2). Upon maturation of the brain, nestin expression is quickly down-regulated and replaced by expression of the neurofilament proteins (2). Because nestin is expressed in both mature and precursor neuronal and glial cells, as well as in the developing brain and in the brain and spinal cord following damage, nestin is widely accepted as a marker of neural stem/progenitor cells (3). Expression of nestin is also found in cells from various nervous system t |
Immunogen | Immunogen: A synthetic peptide of human NES Calculated Molecular Weight: 177kDa |
Other Names | [Nestin: NES; FLJ21841; Nbla00170; Nestin], [NES; NES; Nbla00170] |
Gene, Accession # | [NES], Gene ID: 10763, NCBI: P48681.2, UniProt: P48681 |
Catalog # | MBS125086 |
Price | $275, $430 |
Order / More Info | NES Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |