Mitofusin 2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mitofusin 2 |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.03 mg, 0.1 mg, 0.1 mg |
| Concentration | n/a |
| Applications | Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Is required for PARK2 recruitment to dysfunctional mitochondria. Involved in the control of unfolded protein respon |
| Immunogen | Immunogen: A synthesized peptide derived from human Mitofusin 2. Subcellular Localization: Mitochondrion outer membrane; Multi- pass membrane protein. Colocalizes with BAX during apoptosis. Tissue Specificity: Ubiquitous; expressed at low level. Highly expressed in heart and kidney. |
| Other Names | [Mitofusin-2; 3.6.5.-; Transmembrane GTPase MFN2; MFN2; CPRP1; KIAA0214], [MFN2; MFN2; HSG; MARF; CMT2A; CPRP1; CMT2A2; HMSN6A; CMT2A2A; CMT2A2B; CPRP1; KIAA0214] |
| Gene, Accession # | [MFN2], Gene ID: 9927, NCBI: NP_001121132.1, UniProt: O95140 |
| Catalog # | MBS179335 |
| Price | $160, $340, $340 |
| Order / More Info | Mitofusin 2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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