TAK1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TAK1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse; rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects 67.2 kDa, 40 kDa band is a possible degradation product. TAK1 encoded by the gene MAP3K7, is a protein-serine/threonine kinase that is activated by proinflammatory cytokines and in response to physical/chemical stress, including UVR, osmotic- and oxidative stress. It is a mediator of TRAF6 and TGF-beta signal transduction, and activates IKBKB and MAPK8 in response to TRAF6 signalling. It also stimulates NFkappaB activation and activation of the p38 MAPK pathway. It is responsible for controlling a variety of cell functions such as transcription and apoptosis. TAK1 is important for TGF-beta1 regulation of MMP9 and the metastatic potential of certain breast cancer cell lines. |
| Immunogen | Immunogen: Synthetic peptide of Human TAK1 (400-500 aa), conjugated to Keyhole Limpet Haemocyanin (KLH). Immunogen Species: Human Cellular Localization: Cytoplasm; Cell Membrane; Peripheral Membrane Protein; Cytoplasmic Side Conjugate: Unconjugated Storage Buffer: PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide Tissue Specificity: Isoform 1A is the most abundant in ovary, skeletal muscle, spleen and blood mononuclear cells. Isoform 1B is highly expressed in brain, kidney and small intestine. Isofor |
| Other Names | [Rabbit Human TAK1; MAP3K7; TAK1; Mitogen-activated protein kinase kinase kinase 7; TGF-beta-activated kinase 1; Transforming growth factor-beta-activated kinase 1; MEKK7] |
| Gene, Accession # | [TAK1], Gene ID: 6885, NCBI: NP_003179.1, UniProt: O43318 |
| Catalog # | MBS8000679 |
| Price | $390 |
| Order / More Info | TAK1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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