ADAMTS4 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-ADAMTS4 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | ADAMTS4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit IgG polyclonal antibody for A disintegrin and metalloproteinase with thrombospondin motifs 4(ADAMTS4) detection. Background: ADAMTS4, A disintegrin and metalloproteinase with thrombospondin motifs 4, is an enzyme that in humans is encoded by the ADAMTS4 gene. ADAMTS4 is a member of the large ADAMTS family of zinc-dependent proteases. The human ADAMTS4 gene is mapped to chromosome 1 by somatic cell hybrid analysis. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervo |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ADAMTS4 (813-837aa TPQDWLHRRAQILEILRRRPWAGRK), different from the related mouse sequence by five amino acids, and from the related rat sequence by six amino acids. |
| Other Names | [ADAM TS4; ADAM-TS4; ADAMTS4 protein; ADMP1; ADMP-1; Aggrecanase 1; Aggrecanase1; Aggrecanase-1; ATS4; KIAA 0688; KIAA0688; O75173; A disintegrin and metalloproteinase with thrombospondin motifs 4; ADAM metallopeptidase with thrombospondin type 1 motif, 4], [ADAMTS4; ADAMTS4; ADMP-1; ADAMTS-2; ADAMTS-4; KIAA0688; ADAM-TS 4; ADAM-TS4; ADAMTS-4] |
| Gene, Accession # | [ADAMTS4], Gene ID: 9507, NCBI: NP_001307265.1, UniProt: O75173 |
| Catalog # | MBS178673 |
| Price | $315 |
| Order / More Info | ADAMTS4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Hurskainen, T. L., Hirohata, S., Seldin, M. F., Apte, S. S.ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases: general features and genomic distribution of the ADAM-TS family.J. Biol. Chem. 274: 25555-25563, 1999.2. Tang, B. L., Hong, W.ADAMTS: a novel family of proteases with an ADAM protease domain and thrombospondin 1 repeats.FEBS Lett. 445: 223-225, 1999.3. Tortorella, M. D., Burn, T. C., Pratta, M. A., Abbaszade, I., Hollis, J. M., Liu, R., Rosenfeld, S. A., Copeland, R. A., Decicco, C. P., Wynn, R., Rockwell, A., Yang, F., and 16 others.Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins.Science 284: 1664-1666, 1999. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies