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Antigenic Specificity | FAS |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of SW480 cell lines, using FAS antibody. Immunohistochemistry of paraffin-embedded human kidney using FAS antibody at dilution of 1:400 (200x lens). Immunohistochemistry of paraffin-embedded rat spleen using FAS antibody at dilution of 1:400 (200x lens). Immunohistochemistry of paraffin-embedded mouse kidney using FAS antibody at dilution of 1:400 (200x lens). Association of the receptor Fas with its ligand FasL triggers an apoptotic pathway that plays an important role in immune regulation, development, and progression of cancers (1, 2). Loss of function mutation in either Fas (lpr mice) or FasL (gld mice) leads to lymphadenopathy and splenomegaly as a result of decreased apoptosis in CD4-CD8- |
Immunogen | Immunogen: Recombinant protein of human FAS |
Other Names | n/a |
Gene, Accession # | [FAS] |
Catalog # | MBS419397 |
Price | $385 |
Order / More Info | FAS Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |