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Antigenic Specificity | Myb Sumoylation Site, 506-534 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.32 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Myb Sumoylation Site antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 506-534 amino acids from human Myb Sumoylation Site. Myb is a transcriptional activator; DNA-binding protein that recognizes the sequence 5'-YAAC[GT]G-3'. It participates in the control of proliferation and differentiation of hematopoietic progenitor cells. Myb is a transcription factor related to Myc, and is expressed predominantly in haematopoietic cells and immature gastroepithelial cells. TRAF7 stimulates the sumoylation of Myb at Lys-523 and Lys-499, which are the same sites as those used for PIASy-induced sumoylation. A correlation has been established between reduction in sumoylation of Myb and increase in transcript |
Immunogen | n/a |
Other Names | [Transcriptional activator Myb; Proto-oncogene c-Myb; MYB] |
Gene, Accession # | [MYB], Gene ID: 4602, NCBI: NP_001123644.1, UniProt: P10242 |
Catalog # | MBS9209779 |
Price | $165, $370 |
Order / More Info | Myb Sumoylation Site, 506-534 Antibody from MYBIOSOURCE INC. |
Product Specific References | Luchetti, M.M., et al., J. Biol. Chem. 278(3):1533-1541 (2003). Dahle, O., et al., Eur. J. Biochem. 270(6):1338-1348 (2003). Chen, J., et al., Oncogene 21(12):1859-1869 (2002). Hernandez-Munain, C., et al., J. Immunol. 169(8):4362-4369 (2002). Tanno, B., et al., J. Biol. Chem. 277(26):23172-23180 (2002). |