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Antigenic Specificity | FK-506 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgM |
Format | unconjugated |
Size | 0.25 mg |
Concentration | n/a |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-FK-506 [Murine MAb recognizes conjugated and non-conjugated FK-506.]. This antibody recognizes conjugated and non-conjugated FK-506 (Kd=10-9 M). FK-506 is a novel macrolide with similar, but more potent, immunosuppressant activity than cyclosporine. FK-506 is used for primary or rescue immunosuppression in patients after solid organ transplantation. Clinically relevant side effects of FK-506 administration are nephrotoxicity, neurotoxicity, diabetes mellitus, and hypertension. Most of these side effects are related to blood levels of FK-506 rather than dosage. Therefore, therapeutic drug monitoring of FK-506 is a prerequisite for therapy. The whole blood target level range aimed for in clinical practice is 3.0-20.0 ng/ml a |
Immunogen | Antigen: FK-506 conjugated to bovine serum albumin. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS190166 |
Price | $315 |
Order / More Info | FK-506 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |