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Antigenic Specificity | PBXIP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PBXIP1 antibody detects endogenous levels of PBXIP1. Function: Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling.Subunit Structure: Interacts with TEX11 (By similarity). Interacts with ESR1, PBX1, PBX2 and PBX3.Similarity: The C-terminal domain (AA 443-731) contains a nuclear export signal.Association to the cytoskeleton through a N-terminal leucine rich-domain (AA 190-218). |
Immunogen | Immunogen: A synthesized peptide derived from human PBXIP1. Subcellular Location: Cytoplasm, Cytoskeleton. Nucleus. Note=Shuttles between the nucleus and the cytosol. Mainly localized in the cytoplasm, associated with microtubules. Detected in small amounts in the nucleus. Tissue Specificity: Expressed in early hematopoietic precursors. Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Sheep (100%), Rabbit (100%), Dog (100%) |
Other Names | [4732463H20Rik; Hematopoietic PBX interacting protein; HPIP; MGC38361; Pre B cell leukemia homeobox interacting protein 1; RP11-307C12.2] |
Gene, Accession # | [PBXIP1], Gene ID: 57326, NCBI: NP_001304663.1, UniProt: Q96AQ6 |
Catalog # | MBS9603357 |
Price | $240, $280 |
Order / More Info | PBXIP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |