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Antigenic Specificity | PPP2R5B (C-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Immunofluorescence (IF), ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PPP2R5B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 466-500 amino acids from the C-terminal region of human PPP2R5B. The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The phosphorylated form mediates the interaction between AKT1 and PP2A phosphatase leading to dephosphorylation of AKT1 on the 'Thr-308' and 'Ser-373' residues. |
Immunogen | n/a |
Other Names | [Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform; PP2A B subunit isoform B'-beta; PP2A B subunit isoform B56-beta; PP2A B subunit isoform PR61-beta; PP2A B subunit isoform R5-beta; PPP2R5B] |
Gene, Accession # | [PPP2R5B], Gene ID: 5526, NCBI: NP_006235.1, UniProt: Q15173 |
Catalog # | MBS9209666 |
Price | $165, $370 |
Order / More Info | PPP2R5B (C-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | McCright B.,et al.J. Biol. Chem. 270:26123-26128(1995). Zolnierowicz S.,et al.Biochem. J. 317:187-194(1996). McCright B.,et al.J. Biol. Chem. 271:22081-22089(1996). Kitajima T.S.,et al.Nature 441:46-52(2006). Rodgers J.T.,et al.Mol. Cell 41:471-479(2011). |