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Antigenic Specificity | gamma-synuclein (SNCG) (breast cancer-specific protein 1) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | 1ug/ul |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SNCG (also designated gamma-synuclein or breast cancer-specific protein 1), with 127-amino acid protein (about 14kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals, while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast t |
Immunogen | Immunogen: Ni-NTA purified truncated recombinant SNCG expressed in E Coli strain BL21 (DE3) |
Other Names | [SNCG, partial; Gamma-synuclein], [SNCG] |
Gene, Accession # | NCBI: CAG46589.1 |
Catalog # | MBS418410 |
Price | $445 |
Order / More Info | gamma-synuclein (SNCG) (breast cancer-specific protein 1) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Haiyan Liu, Wei Liu, Yinwei Wu Cancer Res. 2005 Sep 1;65 (17):7635-43 2. Irina Surgucheva, Belinda McMahon, Andrei Surguchov Cell Motil Cytoskeleton. 2006 May 26 |