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Antigenic Specificity | MEK 1 (pSer221) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (expected from sequence), rat (expected from sequence) |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti MEK 1 (pSer221) antibody recognizes MAPK/ERK kinase 1 (MEK 1), also known as dual specificity mitogen-activated protein kinase kinase 1, MAP kinase kinase 1 (MAPKK 1) and ERK activator kinase 1, when phosphorylated at serine 221. MEK 1 is an integral component of the MAP kinase cascade that regulates cell growth and differentiation, and may also play a role in brain synaptic plasticity. MEK1 is phosphorylated at serine 217 and serine 221 by Raf kinases, increasing MEK1 activity (Matallanas et al. 2011) and subsequently leading to activation of ERK1/2. |
Immunogen | Immunogen: Phospho specific-peptide corresponding to residues surrounding serine 221 of human MEK 1 |
Other Names | [MEK 1 (pSer221)], [MAP2K1; MAP2K1; CFC3; MEK1; MKK1; MAPKK1; PRKMK1; MEK1; PRKMK1; MAP kinase kinase 1; MAPKK 1; MKK1; MEK 1] |
Gene, Accession # | [MAP2K1], Gene ID: 5604, NCBI: Q02750.2, UniProt: Q02750 |
Catalog # | MBS225285 |
Price | $375 |
Order / More Info | MEK 1 (pSer221) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |