Edit |   |
---|---|
Antigenic Specificity | MMP-14 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total MMP-14 protein. Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2.Bimal K. Ray, Circ. Res., Nov 2004; 95: 1082 - 1090. Sharon Elliot, Invest. Ophthalmol. Vis. Sci., Apr 2006; 47: 1696 - 1702. Hongqing Q. Ye, Invest. Ophthalmol. Vis. Sci., Sep 2000; 41: 2894. Leanne J. Bakke, Biol Reprod, Jun 2002; 66: 1627. |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from human MMP-14. |
Other Names | [MT1-MMP; MATRIX METALLOPROTEINASE 14; MEMBRANE-TYPE; MEMBRANE-TYPE MATRIX METALLOPROTEINASE 1; matrix metalloproteinase 14 (membrane-inserted).] |
Gene, Accession # | [MMP-14], Gene ID: 4323, NCBI: NP_004986.1, UniProt: P50281 |
Catalog # | MBS9400770 |
Price | $200, $255 |
Order / More Info | MMP-14 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |