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Antigenic Specificity | RHG24 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of RHG24 protein. ARHGAP24 (Rho GTPase Activating Protein 24) is a Protein Coding gene. Diseases associated with ARHGAP24 include Glomerulosclerosis, Focal Segmental, 1 and Atypical Autism. Among its related pathways are G-protein signaling_Regulation of RAC1 activity and p75 NTR receptor-mediated signalling. ARHGAP24 encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human RHG24 protein at amino acid sequence of 550-630 |
Other Names | [Rabbit RHG24; Rho GTPase-activating protein 24; Filamin-A-associated RhoGAP; FilGAP; RAC1-and CDC42-specific GTPase-activating protein of 72 kDa; RC-GAP72; Rho-type GTPase-activating protein 24; RhoGAP of 73 kDa; Sarcoma antigen NY-SAR-88; p73RhoGAP] |
Gene, Accession # | [RHG24], Gene ID: 83478, NCBI: AAH47918.1, UniProt: Q8N264 |
Catalog # | MBS9710704 |
Price | $130, $220, $325 |
Order / More Info | RHG24 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |