Human ATF-2 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human ATF-2 antibody, protein, ELISA kits.
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| Antigenic Specificity | Human ATF-2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The transcription factor ATF-2 (also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins (1). ATF-2 interacts with a variety of viral oncoproteins and cellular tumor suppressors and is a target of the SAPK/JNK and p38 MAP kinase signaling pathways (2-4). Various forms of cellular stress, including genotoxic agents, inflammatory cytokines, and UV irradiation, stimulate the transcriptional activity of ATF-2. Cellular stress activates ATF-2 by phosphorylation of Thr69 and Thr71 (2-4). Both SAPK and p38 MAPK have been shown to phosphorylate ATF-2 at these sites in vitro and in cells transfected with ATF-2. Mutations of these sites result in the loss of stress-induced |
| Immunogen | Immunogen: A fusion protein of human ATF-2 |
| Other Names | [ATF-2 Rabbit pab], [ATF2; CRE-BP1; CREB2; HB16; MGC111558; TREB7] |
| Gene, Accession # | [ATF-2], Gene ID: 1386, NCBI: NP_001243019.1, UniProt: P15336 |
| Catalog # | MBS125207 |
| Price | $275, $430 |
| Order / More Info | Human ATF-2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Abdel-Hafiz, H.A. et al. (1992) Mol. Endocrinol. 6, 2079-2089.2. Gupta, S. et al. (1995) Science 267, 389-393.3. van Dam, H. et al. (1995) EMBO J. 14, 1798-1811.4. Livingstone, C. et al. (1995) EMBO J. 14, 1785-1797. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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