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Antigenic Specificity | ICAM1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Intercellular cell adhesion molecule-1 (CD54 or ICAM-1) is a cell surface glycoprotein that belongs to the immunoglobulin superfamily (IgSF) of adhesion molecules. CD54 is expressed at low levels in diverse cell types, and is induced by cytokines (TNF-alpha, interleukin-1) and bacterial lipopolysaccharide (1). Apical localization of CD54 on endothelial cells (or basolateral localization on epithelial cells) is a prerequisite for leukocyte trafficking through the endothelial (or epithelial) barrier (1). Apical expression of CD54 on epithelial cells mediates pathogen invasion as well as host defense, a pattern also observed in tumors (1). CD54 also functions as a co-stimulator on antigen presenting cells, binding to its receptor LFA-1 (leukoc |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [CD54: CD54; Icam-1; Ly-47; MALA-2; MGC6195; Icam1], [Icam1; Icam1; CD54; Ly-47; Icam-1; MALA-2; Icam-1; ICAM-1] |
Gene, Accession # | [ICAM1], Gene ID: 15894, NCBI: P13597.1, UniProt: P13597 |
Catalog # | MBS125051 |
Price | $235, $350, $525 |
Order / More Info | ICAM1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |