Edit |   |
---|---|
Antigenic Specificity | ATG7 |
Clone | 3D6 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous ATG7 protein. ATG7 (autophagy related 7) encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. |
Immunogen | Immunogen: Recombinant Protein of ATG7 |
Other Names | [Mouse ATG7 Mouse (3D6); Ubiquitin-like modifier-activating enzyme ATG7; ATG12-activating enzyme E1 ATG7; Autophagy-related protein 7; APG7-like; hAGP7; Ubiquitin-activating enzyme E1-like protein] |
Gene, Accession # | [ATG7], Gene ID: 10533, NCBI: NP_001129503.2, UniProt: O95352 |
Catalog # | MBS9700599 |
Price | $130, $220, $325 |
Order / More Info | ATG7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |