Edit |   |
---|---|
Antigenic Specificity | Phospho-IGFBP-3 (Ser183) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-IGFBP-3 (Ser183) antibody detects endogenous levels of IGFBP-3 only when phosphorylated at Serine 183. Description: This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II.Function: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and |
Immunogen | Immunogen: A synthesized peptide derived from human IGFBP-3 around the phosphorylation site of Serine 183 Subcellular Location: Secreted. Tissue Specificity: Expressed by most tissues. Present in plasma. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Dog (100%) |
Other Names | [Acid stable subunit of the 140 K IGF complex; Binding protein 29; Binding protein 53; BP 53; BP53; Growth hormone dependent binding protein; IBP 3; IBP-3; IBP3; IBP3_HUMAN; IGF binding protein 3; IGF-binding protein 3; IGFBP 3; IGFBP-3; IGFBP3; Insulin Like Growth Factor Binding Protein 3; Insulin-like growth factor binding protein 3 precursor; Insulin-like growth factor-binding protein 3] |
Gene, Accession # | [IGFBP-3], Gene ID: 3486, NCBI: NP_000589.2, UniProt: P17936 |
Catalog # | MBS9600974 |
Price | $240, $280 |
Order / More Info | Phospho-IGFBP-3 (Ser183) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |