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Antigenic Specificity | Aven |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, monkey |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Aven Polyclonal Antibody detects endogenous levels of Aven protein. AVEN, a cell death regulator, is an important signal inducer in acute leuke-mias. AVEN is a highly conserved peripheral membrane protein that protects the cell against the proteolytic activation of caspases as well as Apaf-1 mediated apoptosis by interfering with Apaf-1's ability to self-associate. Bcl-2 and Bad also interact with AVEN to prevent apoptosis. AVEN is highly expressed in ovary, heart, thymus, spleen, testis and colon, but can also be detected in other tissues. Erythropoietin and methylprednisolone may play important roles in the expression of AVEN in cardiac tissue, especially after a traumatic brain injury. In young patients suffering from acute |
Immunogen | Immunogen: Synthesized peptide derived from the C-terminal region of human Aven at AA range: 270-350 |
Other Names | [Rabbit Aven; Cell death regulator Aven] |
Gene, Accession # | [AVEN], Gene ID: 57099, NCBI: NP_065104.1, UniProt: Q9NQS1 |
Catalog # | MBS9701468 |
Price | $130, $220, $325 |
Order / More Info | Aven Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |