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Antigenic Specificity | CY24B - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against CYBB. It was validated on Western Blot using a cell lysate as a positive control.Target Description: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxyg |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CY24B |
Other Names | [cytochrome b-245 heavy chain; Cytochrome b-245 heavy chain; cytochrome b-245 heavy chain; cytochrome b-245 beta chain; CGD91-phox; Cytochrome b(558) subunit beta; Cytochrome b558 subunit beta; Heme-binding membrane glycoprotein gp91phox; NADPH oxidase 2; Neutrophil cytochrome b 91 kDa polypeptide; Superoxide-generating NADPH oxidase heavy chain subunit; gp91-1; gp91-phox; p22 phagocyte B-cytochrome] |
Gene, Accession # | [CYBB], Gene ID: 1536, NCBI: NP_000388, UniProt: P04839 |
Catalog # | MBS3207292 |
Price | $365 |
Order / More Info | CY24B - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |