NR1D1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNR1D1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunoprecipitation (IP)
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DescriptionReverse orientation c-erbA gene alpha (Rev-erbalpha, EAR-1, or NR1D1) is a widely expressed member of the orphan nuclear receptor family of proteins (1). Rev-erbalpha is highly expressed in adipose tissue, skeletal muscle, brain and liver, and regulates cellular proliferation and differentiation. Expression increases during differentiation in adipocytes and ectopic expression of Rev-erbalpha potentiates the adipocyte differentiation of 3T3-L1 cells (2). In addition, expression oscillates with circadian rhythm in liver cells and Rev-erbalpha regulates expression of BMAL1, ApoA-I and ApoC-III, all key regulators of circadian rhythm (3,4,5,6,7). Phosphorylation of Rev-erbalpha Ser55 and Ser59 by GSK3beta appears to stabilize Rev-erbalpha prote
ImmunogenImmunogen: Recombinant Protein
Other Names[Rev-erbalpha: Rev-erba; NR1D1; EAR1; THRA1; THRAL; ear-1; hRev], [NR1D1; NR1D1; EAR1; hRev; THRA1; THRAL; ear-1; EAR1; HREV; THRAL; EAR-1]
Gene, Accession #[NR1D1], Gene ID: 9572, NCBI: P20393.1, UniProt: P20393
Catalog #MBS127846
Price$235, $350
Order / More InfoNR1D1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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