INS Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityINS
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
IsotypeIgG
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionAfter removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.
ImmunogenImmunogen: Recombinant protein of human INS
Other Names[IDDM; IDDM1; IDDM2; ILPR; IRDN; MODY10]
Gene, Accession #[INS], Gene ID: 3630, NCBI: P01308.1, UniProt: P01308
Catalog #MBS9131233
Price$235, $350, $525
Order / More InfoINS Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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