DMRT1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDMRT1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatperoxidase (HRP) conjugate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionTranscription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and promotes spermatogonial development by activating spermatogonial differentiation genes, such as SOHLH1. Also plays a key role in postnatal sex maintenance by maintaining testis determination and preventing feminizat
ImmunogenImmunogen: Recombinant Human Doublesex- and mab-3-related transcription factor 1 protein (195-363AA)
Other Names[Doublesex- and mab-3-related transcription factor 1; DM domain expressed in testis protein 1; DMRT1; DMT1]
Gene, Accession #[DMRT1], Gene ID: 1761, NCBI: NP_068770.2, UniProt: Q9Y5R6
Catalog #MBS7051649
Price$160, $235
Order / More InfoDMRT1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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