Edit |   |
---|---|
Antigenic Specificity | DMRT1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and promotes spermatogonial development by activating spermatogonial differentiation genes, such as SOHLH1. Also plays a key role in postnatal sex maintenance by maintaining testis determination and preventing feminizat |
Immunogen | Immunogen: Recombinant Human Doublesex- and mab-3-related transcription factor 1 protein (195-363AA) |
Other Names | [Doublesex- and mab-3-related transcription factor 1; DM domain expressed in testis protein 1; DMRT1; DMT1] |
Gene, Accession # | [DMRT1], Gene ID: 1761, NCBI: NP_068770.2, UniProt: Q9Y5R6 |
Catalog # | MBS7051649 |
Price | $160, $235 |
Order / More Info | DMRT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |