PKCbeta II Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | PKCbeta II |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to Human PKCbeta II. Activation of protein kinase C (PKC) is one of the earliest events in a cascade that controls a variety of cellular responses, including secretion, gene expression, proliferation, and muscle contraction (1,2). PKC isoforms belong to three groups based on calcium dependency and activators. Classical PKCs are calcium-dependent via their C2 domains and are activated by phosphatidylserine (PS), diacylglycerol (DAG), and phorbol esters (TPA, PMA) through their cysteine-rich C1 domains. Both novel and atypical PKCs are calcium-independent, but only novel PKCs are activated by PS, DAG, and phorbol esters (3-5). Members of these three PKC groups contain a pseudo-substrate or autoinhibitory domain that binds to |
| Immunogen | Immunogen: A fusion protein of human PKCbeta II |
| Other Names | [PRKCB; PKCbeta II; PKCbeta II; PRKCB; MGC41878; PKC-beta; PKCB; PRKCB1; PRKCB2;], [PRKCB; PRKCB; PKCB; PRKCB1; PRKCB2; PKC-beta; PKCB; PRKCB1; PKC-B; PKC-beta] |
| Gene, Accession # | Gene ID: 5579, NCBI: NP_002729.2, UniProt: P05771 |
| Catalog # | MBS125510 |
| Price | $275, $430 |
| Order / More Info | PKCbeta II Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Nishizuka, Y. (1984) Nature 308, 693-698. 2. Keranen, L.M. et al. (1995) Curr. Biol. 5, 1394-1403. 3. Mellor, H. and Parker, P.J. (1998) Biochem J. 332 (Pt 2), 281-292. 4. Ron, D. and Kazanietz, M.G. (1999) FASEB J. 13, 1658-1676. 5. Moscat, J. and Diaz-Meco, M.T. (2000) EMBO Rep. 1, 399-403. 6. Baron, C.L. and Malhotra, V. (2002) Science 295, 325-328. 7. Flynn, P. et al. (2000) J. Biol. Chem. 275, 11064-11070 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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