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Antigenic Specificity | CD20 / MS4A1 (B-Cell Marker) |
Clone | [SPM494] |
Host Species | Mouse |
Reactive Species | human, baboon, monkey. does not react with cow, dog, porcine, and rat |
Isotype | IgG2a, kappa |
Format | unconjugated |
Size | 0.1 mL, 0.5 mL |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a protein of 30-33kDa, which is identified as CD20. Its epitope is located in the cytoplasmic domain of CD20 and was, therefore, ascribed as CD20cy in the 5th Workshop. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their |
Immunogen | Immunogen: Human tonsil B cells |
Other Names | [APY; ATOPY; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; Bp35; Fc epsilon receptor I beta chain; Fc Fragment of IgE high affinity I receptor for beta polypeptide; FCER1B; High affinity immunoglobulin epsilon receptor subunit beta; IgE Fc receptor subunit beta; IGEL; IGER; IGHER; LEU16; Leukocyte surface antigen Leu-16; Ly44; Membrane spanning 4 domains subfamily A member 2; Membrane-spanning 4-domains subfamily A member 1 (MS4A1)], [MS4A1; MS4A1; B1; S7; Bp35; CD20; CVID5; MS4A2; LEU-16; CD20] |
Gene, Accession # | [MS4A1], Gene ID: 931, NCBI: NP_068769.2, UniProt: P11836 |
Catalog # | MBS438617 |
Price | $190, $340 |
Order / More Info | CD20 / MS4A1 (B-Cell Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Schlossman, S., et al., eds. 1995. Leucocyte Typing V. New York: Oxford University Press. |