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Antigenic Specificity | NKX2-1 (Center), 2-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This NKX2-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-226 amino acids from the Central region of human NKX2-1. This gene encodes a protein initially identified as athyroid-specific transcription factor. The encoded protein binds tothyroglobulin promoter and regulates the expression ofthyroid-specific genes but has also been shown to regulate theexpression of genes involved in morphogenesis. Mutations anddeletions in this gene are associated with benign hereditarychorea, choreoathetosis, congenital hypothyroidism, and neonatalrespiratory distress, and may be associated with thyroid cancer.Multiple transcript variants encoding different isoforms have been |
Immunogen | n/a |
Other Names | [Homeobox protein Nkx-21; Homeobox protein NK-2 homolog A; Thyroid nuclear factor 1; Thyroid transcription factor 1; TTF-1; Thyroid-specific enhancer-binding protein; T/EBP; NKX2-1; NKX2A; TITF1; TTF1] |
Gene, Accession # | [NKX2-1], Gene ID: 7080, NCBI: NP_001073136.1, UniProt: P43699 |
Catalog # | MBS9201746 |
Price | $165, $370 |
Order / More Info | NKX2-1 (Center), 2-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | Kim, J.H., et al. Acta Cytol. 54(3):277-282(2010) Xu, B., et al. Appl. Immunohistochem. Mol. Morphol. 18(3):244-249(2010) Narumi, S., et al. J. Clin. Endocrinol. Metab. 95(4):1981-1985(2010) Guillot, L., et al. Hum. Mutat. 31 (2), E1146-E1162 (2010) : Cantara, S., et al. Thyroid Res 3 (1), 4 (2010) : |