NKX2-1 (Center), 2-1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNKX2-1 (Center), 2-1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: mouse, rat)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis NKX2-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-226 amino acids from the Central region of human NKX2-1. This gene encodes a protein initially identified as athyroid-specific transcription factor. The encoded protein binds tothyroglobulin promoter and regulates the expression ofthyroid-specific genes but has also been shown to regulate theexpression of genes involved in morphogenesis. Mutations anddeletions in this gene are associated with benign hereditarychorea, choreoathetosis, congenital hypothyroidism, and neonatalrespiratory distress, and may be associated with thyroid cancer.Multiple transcript variants encoding different isoforms have been
Immunogenn/a
Other Names[Homeobox protein Nkx-21; Homeobox protein NK-2 homolog A; Thyroid nuclear factor 1; Thyroid transcription factor 1; TTF-1; Thyroid-specific enhancer-binding protein; T/EBP; NKX2-1; NKX2A; TITF1; TTF1]
Gene, Accession #[NKX2-1], Gene ID: 7080, NCBI: NP_001073136.1, UniProt: P43699
Catalog #MBS9201746
Price$165, $370
Order / More InfoNKX2-1 (Center), 2-1 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesKim, J.H., et al. Acta Cytol. 54(3):277-282(2010) Xu, B., et al. Appl. Immunohistochem. Mol. Morphol. 18(3):244-249(2010) Narumi, S., et al. J. Clin. Endocrinol. Metab. 95(4):1981-1985(2010) Guillot, L., et al. Hum. Mutat. 31 (2), E1146-E1162 (2010) : Cantara, S., et al. Thyroid Res 3 (1), 4 (2010) :
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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