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Antigenic Specificity | Ep-CAM/CD326 (Epithelial Marker) |
Clone | [rMOC-31] |
Host Species | Mouse |
Reactive Species | human.does not react with rat. |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Binding epitope of this antibody is located in the first EGF-like repeat domain (EGF1) between amino acids 27-59 of Ep-CAM. EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas with the exception of adult squamous epithelium, hepatocytes and gastric epithelial cells. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma. |
Immunogen | Immunogen: Neuraminidase treated GLS-1 human small cell lung carcinoma cells Cellular Localization: Cell Surface |
Other Names | [Adenocarcinoma-associated Antigen; Cell Surface Glycoprotein Trop-1; EGP2; EGP314; EGP40; Epithelial Cell Adhesion Molecule; Epithelial Glycoprotein 314; ESA; KSA; TACD1; TROP1; Tumor-associated Calcium Signal Transducer 1 (TACSTD1); ECS-1; Epidermal Surface Antigen 1; ESA1; FLOT2; Flotillin-2; Membrane Component, Chromosome 17, Surface Marker-1 (M17S1); REG-1; Reggie-1; Reggie-2] |
Gene, Accession # | [Ep-CAM], Gene ID: 4072, NCBI: NP_002345.2, UniProt: P16422 |
Catalog # | MBS4380092 |
Price | $190, $340, $340 |
Order / More Info | Ep-CAM/CD326 (Epithelial Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Manon J. Winter, Iris D. Nagtegaal, J. Han J. M. van Krieken, and Sergey V. Litvinov. The Epithelial Cell Adhesion Molecule (Ep-CAM) as a Morphoregulatory Molecule Is a Tool in Surgical Pathology. J Biol Chem 125:437-446 (1994). Postmus PE, Hirschler-Schulte TJ, De Leij L, Poppema S, Elema JE, Edens ET, Mesander G, Sluiter HJ, The TH. 1986. Diagnostic application of a monoclonal antibody against small cell lung cancer. Cancer. 57:60-3. |