MACROD1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMACROD1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein G purified
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC)
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DescriptionRemoves ADP-ribose from glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Plays a role in estrogen signaling. Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen. May play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. Could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction. Could be involved in invasive growth by down-regulating
ImmunogenImmunogen: Recombinant human O-acetyl-ADP-ribose deacetylase MACROD1 protein
Other Names[O-acetyl-ADP-ribose deacetylase MACROD1 (EC:3.2.2.-; EC:3.5.1.-); MACROD1; LRP16; MACRO domain-containing protein 1; Protein LRP16; [Protein ADP-ribosylglutamate] hydrolase], [MACROD1; MACROD1; LRP16; LRP16]
Gene, Accession #[MACROD1], Gene ID: 28992, NCBI: NP_054786.2, UniProt: Q9BQ69
Catalog #MBS1492387
Price$160, $235
Order / More InfoMACROD1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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