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Antigenic Specificity | MACROD1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Removes ADP-ribose from glutamate residues in proteins bearing a single ADP-ribose moiety. Inactive towards proteins bearing poly-ADP-ribose. Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins. Plays a role in estrogen signaling. Binds to androgen receptor (AR) and amplifies the transactivation function of AR in response to androgen. May play an important role in carcinogenesis and/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. Could be an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction. Could be involved in invasive growth by down-regulating |
Immunogen | Immunogen: Recombinant human O-acetyl-ADP-ribose deacetylase MACROD1 protein |
Other Names | [O-acetyl-ADP-ribose deacetylase MACROD1 (EC:3.2.2.-; EC:3.5.1.-); MACROD1; LRP16; MACRO domain-containing protein 1; Protein LRP16; [Protein ADP-ribosylglutamate] hydrolase], [MACROD1; MACROD1; LRP16; LRP16] |
Gene, Accession # | [MACROD1], Gene ID: 28992, NCBI: NP_054786.2, UniProt: Q9BQ69 |
Catalog # | MBS1492387 |
Price | $160, $235 |
Order / More Info | MACROD1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |