Edit |   |
---|---|
Antigenic Specificity | BIN1 |
Clone | [BN-1] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2b |
Format | ascites |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Formalin, Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Mouse IgG monoclonal antibody for BIN1, bridging integrator 1 (BIN1) detection. Tested with WB, IHC-F, ICC in Human, mouse, rat. No cross reactivity with other proteins. Uniprot ID: O00499 Background: BIN1(AMPH2) is a novel human gene product with features of a tumor suppressor protein. BIN1 gene to chromosome 2q14. Loss of BIN1 expression appears to be a frequent aberration in human hepatocellular carcinomas. mutations in BIN1 cause centronuclear myopathy by interfering with remodeling of T tubules and/or endocytic membranes, and that the functional interaction between BIN1 and DNM2 is necessary for normal muscle function and positioning of nuclei. |
Immunogen | Immunogen: Recombinant polypeptide containing amino acids 189-398 of human Bin1. |
Other Names | [Myc box-dependent-interacting protein 1; bridging integrator 1; AMPHL; AMPH2; SH3P9; amphiphysin II; Amphiphysin-like protein; Box-dependent myc-interacting protein 1; Bridging integrator 1], [BIN1; BIN1; AMPH2; AMPHL; SH3P9; AMPHL] |
Gene, Accession # | [BIN1], Gene ID: 274, NCBI: O00499.1, UniProt: O00499 |
Catalog # | MBS175043 |
Price | $315 |
Order / More Info | BIN1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |