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Antigenic Specificity | Hepatitis C virus genotype 1a Genome polyprotein |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | Hepatitis C virus genotype 1a |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Core protein packages viral RNA to form a viral nucleocapsid, and promotes virion budding. Modulates viral translation initiation by interacting with HCV IRES and 40S ribosomal subunit. Also regulates many host cellular functions such as signaling pathways and apoptosis. Prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by inducing human STAT1 degradation. Thought to play a role in virus-mediated cell transformation leading to hepatocellular carcinomas. Interacts with, and activates STAT3 leading to cellular transformation. May repress the promoter of p53, and sequester CREB3 and SP110 isoform 3/Sp110b in the cytoplasm. Also represses cell cycle |
Immunogen | Immunogen: Recombinant Hepatitis C virus genotype 1a Genome polyprotein protein(192-325aa) |
Other Names | [Capsid protein C; p21; gp32; gp35; NS1; gp68; gp70; p23; Hepacivirin; NS3P; p70; NS4A; NS4B; p27; NS5A; p56; NS5B; p68], [p23; NS4A; NS4B; NS5A] |
Gene, Accession # | NCBI: P26664.3, UniProt: P26664 |
Catalog # | MBS969103 |
Price | $160, $235 |
Order / More Info | Hepatitis C virus genotype 1a Genome polyprotein Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |