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Antigenic Specificity | CD10 (Membrane Metalloendopeptidase) |
Clone | [MME/1870] |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG2c, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a 100kDa glycoprotein, identified as CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epit |
Immunogen | Immunogen: Recombinant human CD10 protein fragment (aa297-483) Cellular Localization: Cell Surface and Cytoplasmic |
Other Names | [Atriopeptidase; Common acute lymphocytic leukemia antigen (CALLA); Enkephalinase (EPN); gp100; Membrane metalloendopeptidase (MME); Neprilysin; Neutral endopeptidase (NEP); Skin fibroblast elastase (SFE)] |
Gene, Accession # | [CD10], Gene ID: 4311, NCBI: NP_000893.2, UniProt: P08473 |
Catalog # | MBS4380462 |
Price | $190, $340, $340 |
Order / More Info | CD10 (Membrane Metalloendopeptidase) Antibody from MYBIOSOURCE INC. |
Product Specific References | s Moritani S., et al. Mod Pathol 2002; 15(4):397-405. |