IRAK-M Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIRAK-M
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionSpecificity: IRAK-M antibody has no cross response to IRAK or IRAK2. IRAK-M Antibody: Interleukin-1 (IL-1) and lipopolysaccharide (LPS) induces cellular response through IL-1 receptor (IL-1R) and Toll like receptors (TLR). IL-1 receptor-associated kinase (IRAK and IRAK2) mediates the activation of NF-betaB by IL-1/Toll receptors, which is a pivotal transcription factor mediating inflammatory and immune response. A novel member in the IRAK/Pelle family was recently identified and designated IRAK-M. IRAKs associate with IL-1/Toll receptors after IL-1 or LPS stimulation and the dominant negative mutants of IRAKs inhibit IL-1 or LPS induced NF-betaB activation. Members in IRAK/Pelle family play a central role in IL-1R/TLR mediated inflammatory
ImmunogenImmunogen: IRAK-M antibody was raised against a peptide corresponding to amino acids from the carboxy terminus of human IRAK-M. Buffer: IRAK-M Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[IRAK-M; ASRT5; IRAKM; Interleukin-1 receptor-associated kinase 3; IL-1 receptor-associated kinase M; IRAK-3; interleukin-1 receptor-associated kinase 3], [IRAK3; IRAK3; ASRT5; IRAKM; IRAK-3; IRAK-M]
Gene, Accession #[IRAK3], Gene ID: 11213, NCBI: AF113136, UniProt: Q9Y616
Catalog #MBS150500
Price$375
Order / More InfoIRAK-M Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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