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Antigenic Specificity | GANP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total GANP protein. Isoform GANP:Essential for the generation of high-affinity B-cells against T-cell-dependent antigens by affecting somatic hypermutation at the IgV-regions. May have stimulation-dependent DNA primase activity that would generate extra RNA primers in very rapidely proliferating cells and would support clonal expansion of differentiating B-cells By similarity. Involved in the nuclear export of poly(A)-containing mRNAs by acting as a scaffold for the TREX-2 complex. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from human GANP. |
Other Names | [80 kda MCM3-associated protein; GANP protein; KIAA0572; MAP80; MCM3A] |
Gene, Accession # | [GANP], Gene ID: 8888, NCBI: NP_003897.2, UniProt: O60318 |
Catalog # | MBS9402671 |
Price | $200, $255 |
Order / More Info | GANP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |