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Antigenic Specificity | Caspase-2 |
Clone | 4-1-5 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human caspase-2. Detects bands of ~47kDa (full length) and ~14kDa (cleaved) by Western blot. The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or executioner caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological chan |
Immunogen | Immunogen: Recombinant full length human Caspase-2. |
Other Names | [Caspase-2; Caspase-2; caspase-2; caspase 2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2], [CASP2; CASP2; ICH1; NEDD2; CASP-2; NEDD-2; PPP1R57; ICH1; NEDD2; CASP-2; NEDD-2] |
Gene, Accession # | Gene ID: 835, NCBI: P42575.2, UniProt: P42575 |
Catalog # | MBS565033 |
Price | $400 |
Order / More Info | Caspase-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |