Caspase-2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCaspase-2
Clone4-1-5
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein G purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionRecognizes human caspase-2. Detects bands of ~47kDa (full length) and ~14kDa (cleaved) by Western blot. The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or executioner caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological chan
ImmunogenImmunogen: Recombinant full length human Caspase-2.
Other Names[Caspase-2; Caspase-2; caspase-2; caspase 2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2], [CASP2; CASP2; ICH1; NEDD2; CASP-2; NEDD-2; PPP1R57; ICH1; NEDD2; CASP-2; NEDD-2]
Gene, Accession #Gene ID: 835, NCBI: P42575.2, UniProt: P42575
Catalog #MBS565033
Price$400
Order / More InfoCaspase-2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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