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Antigenic Specificity | NAIP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Minor, lower molecular weight bands may represent alternately spliced forms. Neuronal apoptosis inhibitor protein (NAIP) was the first human inhibitor of apoptosis protein (IAP) identified and was discovered by its association with the neurodegenerative disorder spinal muscular atrophy. Members of the IAP family contain one to three copies of an approximately 70 amino acid motif termed baculovirus IAP repeat (BIR); these BIRs promote protein-protein interactions with various caspases such as caspase-3, -7, and -9 as well as members of the TRAF family of signal molecules (reviewed in 3). Unlike other IAPs however, NAIP requires ATP to bind caspase-9 and is not inhibited by the IAP-inhibiting molecule Smac/DIABLO, suggesting that |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a synthetic peptide corresponding to 13 amino acids at the C-terminus of human NAIP. |
Other Names | [neuronal apoptosis inhibitory protein; Baculoviral IAP repeat-containing protein 1; baculoviral IAP repeat-containing protein 1; NLR family, apoptosis inhibitory protein; Neuronal apoptosis inhibitory protein] |
Gene, Accession # | [NAIP], Gene ID: 4671, NCBI: AAC52047 |
Catalog # | MBS9405374 |
Price | $320 |
Order / More Info | NAIP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |