TRIM14 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TRIM14 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: TRIM14 antibody detects endogenous levels of TRIM14. Function: Plays a role in the innate immune defense against viruses. Facilitates the type I IFN response by interacting with MAVS at the outer mitochondria membrane and thereby recruiting NF-kappa-B essential modulator IKBKG/NEMO to the MAVS signalosome, leading to the activation of both the IFN regulatory factor 3/IRF3 and NF-kappa-B pathways (PubMed:24379373). Positively regulates the CGAS-induced type I interferon signaling pathway by stabilizing CGAS and inhibiting its autophagic degradation (PubMed:27666593).Subunit Structure: Interacts with MAVS (PubMed:24379373). Interacts with WRNIP1 and PPP6C; these interactions positively regulate the RIG-I/DDX58 signaling pathw |
| Immunogen | Immunogen: A synthesized peptide derived from human TRIM14. Subcellular Location: Mitochondrion Tissue Specificity: Highest expression in liver; undetectable in skeletal muscle. Predicted Cross Reactivity: Pig, Bovine, Rabbit Similarity: Pig (91%), Bovine (90%), Rabbit (100%) |
| Other Names | [5830400N10Rik; KIAA0129; pub; TRI14_HUMAN; TRIM14; tripartite motif protein 14; tripartite motif protein TRIM14; tripartite motif-containing 14; Tripartite motif-containing protein 14] |
| Gene, Accession # | [TRIM14], Gene ID: 9830, NCBI: NP_055603.2, UniProt: Q14142 |
| Catalog # | MBS9603718 |
| Price | $240, $280 |
| Order / More Info | TRIM14 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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