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Antigenic Specificity | ABHD12 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ABHD12 Polyclonal Antibody detects endogenous levels of ABHD12 protein. ABHD12 encodes an enzyme (abhydrolase domain containing 12) that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in ABHD12 are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encodi |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human ABHD12 at AA range: 200-280 |
Other Names | [Rabbit ABHD12; ABHD12; C20orf22; Monoacylglycerol lipase ABHD12; 2-arachidonoylglycerol hydrolase; Abhydrolase domain-containing protein 12] |
Gene, Accession # | [ABHD12], Gene ID: 26090, NCBI: NP_001035937.1, UniProt: Q8N2K0 |
Catalog # | MBS9701310 |
Price | $130, $220, $325 |
Order / More Info | ABHD12 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |