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Antigenic Specificity | MET |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Met, a high affinity tyrosine kinase receptor for hepatocyte growth factor (HGF, also known as scatter factor) is a disulfide-linked heterodimer made of 45 kDa alpha- and 145 kDa beta-subunits (1,2). The alpha-subunit and the amino-terminal region of the beta-subunit form the extracellular domain. The remainder of the beta-chain spans the plasma membrane and contains a cytoplasmic region with tyrosine kinase activity. Interaction of Met with HGF results in autophosphorylation at multiple tyrosines, which recruit several downstream signaling components, including Gab1, c-Cbl, and PI3 kinase (3). These fundamental events are important for all of the biological functions involving Met kinase activity. The addition of a phosphate at cytoplasmic |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [Met: MET; AUTS9; HGFR; RCCP2; c-Met], [MET; MET; HGFR; AUTS9; RCCP2; c-Met; HGF receptor; SF receptor] |
Gene, Accession # | [MET], Gene ID: 4233, NCBI: P08581.4, UniProt: P08581 |
Catalog # | MBS125613 |
Price | $200, $275, $430 |
Order / More Info | MET Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |