MKNK1 (N-term), 1-30 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMKNK1 (N-term), 1-30
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: mouse)
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 2
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis MKNK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MKNK1. MKNK1 encodes a predicted 424-amino acid protein containing a sequence typical of the catalytic domain of serine/threonine kinases and a putative N-terminal nuclear localization signal sequence.C-terminal region of MKNK1 was phosphorylated and activated in vivo and in vitro by ERK1 and p38 MAP kinases, but not by JNK/SAPK. The activated ERK is essential for the activation of MKNK1 in insect cells. MKNK1 was activated following stimulation of HeLa cells with a variety of extracellular stimuli. MNK1 bind tightly to the growth factor-regulated MAP kinases, Erk1 and Erk2, and also bi
Immunogenn/a
Other Names[MAP kinase-interacting serine/threonine-protein kinase 1; MAP kinase signal-integrating kinase 1; MAPK signal-integrating kinase 1; Mnk1; MKNK1; MNK1]
Gene, Accession #[MKNK1], Gene ID: 8569, NCBI: NP_001129025.1, UniProt: Q9BUB5
Catalog #MBS9203656
Price$165, $370
Order / More InfoMKNK1 (N-term), 1-30 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesOrton, K.C., et al., J. Biol. Chem. 279(37):38649-38657 (2004). Cuesta, R., et al., J. Virol. 78(14):7707-7716 (2004). Knauf, U., et al., Mol. Cell. Biol. 21(16):5500-5511 (2001). Cuesta, R., et al., Genes Dev. 14(12):1460-1470 (2000). Fukunaga, R., et al., EMBO J. 16(8):1921-1933 (1997).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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