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Antigenic Specificity | IL2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | f Fas on CD4+ T cells (3). The effects of IL-2 are mediated through a trimeric receptor complex consisting of IL-2Ralpha, IL-2Rbeta and the common gamma chain, gammac (1,2). IL-2 Ralpha binds exclusively to IL-2 with low affinity and increases binding affinity of the whole receptor complex including IL-2Rbeta and gammac subunits. IL-2Rbeta is also used by IL-15 (1,2). The common gammac is used by other cytokines including IL-4, IL-7, IL-9, IL-15, and IL-21 (1,2). Binding of IL-2 initiates signaling cascades involving Jak1, Jak3, Stat5 and the PI3K/Akt pathways (1,2). |
Immunogen | Immunogen: Recombinant protein of human IL2 Calculated Molecular Weight: 18kDa |
Other Names | [Interleukin-2: IL2; IL-2; TCGF; lymphokine], [IL2; IL2; IL-2; TCGF; lymphokine; IL-2; TCGF] |
Gene, Accession # | [IL2], Gene ID: 3558, NCBI: P60568.1, UniProt: P60568 |
Catalog # | MBS126083 |
Price | $200, $275, $430 |
Order / More Info | IL2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |