IRF3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | IRF3 |
| Clone | [1522CT766.58.24] |
| Host Species | Mouse |
| Reactive Species | human, African Green monkey |
| Isotype | IgG1, k |
| Format | unconjugated |
| Size | 0.05 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This IRF3 antibody is generated from a mouse immunized with a recombinant protein. Key transcriptional regulator of type I interferon (IFN)-dependent immune responses which plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Acts as a more potent activator of the IFN-beta (IFNB) gene than the IFN-alpha (IFNA) gene and plays a critical role in both the early and late phases of the IFNA/B gene induction. Found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA (dsRNA), or to |
| Immunogen | n/a |
| Other Names | [Purified Mouse (Mab); Interferon regulatory factor 3; IRF-3; IRF3] |
| Gene, Accession # | [IRF3], Gene ID: 3661, NCBI: NP_001184051.1, UniProt: Q14653 |
| Catalog # | MBS9215402 |
| Price | $165, $370 |
| Order / More Info | IRF3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Au W.W.-C.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:11657-11661(1995). Tabata Y.,et al.Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). Grimwood J.,et al.Nature 428:529-535(2004). Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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